ADME test in vitro ◊ Physical and chemical ◊ Absorption test ◊ Distribution test ◊ Metabolic research ◊ Transporter study
Pharmacokinetic test ◊ Plasma pharmacokinetics ◊ Bioavailability ◊ Tissue distribution ◊ PK/PD research
ADME test in vivo ◊ Isotopic labeling ◊ Quantitative study of organizational distribution ◊ Excretory pathway research ◊ Metabolite identification ◊ Human absorption and excretion
advantage
◊ ADME tests are available in both vitro and vivo ◊ The pharmacokinetic test involved rodents, rabbits, dogs, monkeys, miniature pigs and other animal species ◊ Pharmacokinetic tests provide a variety of drug delivery pathways, biological samples research and analytical materials research ◊ Successfully passed the biological sample detection ability verification, obtained the ability verification certificate issued by the China national inspection institute ◊ An experienced team of pharmacokinetics researchers can provide all-around support and advance from drug development to clinical registration ◊ Supporting drug requirements from early screening to declaration