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Service

Pre-clinical Safety Evaluation

Service project

◊ Single dose toxicity test (rodents, non-rodents)；
◊ Repeated toxicity tests (rodents, non-rodents)；
◊ Genotoxicity test (Ames test, chromosome aberration test, micronucleus test, mouse lymphoma TK site test)；
◊ Carcinogenicity test；
◊ Immunogenicity test；
◊ Immunotoxicity test；
◊ Drug dependence test；
◊ Reproductive toxicity test General reproductive toxicity test (sectionⅠ) Teratogenic sensitive period toxicity test (sectionⅡ) Perinatal toxicity test (sectionⅢ)；
◊ Safety pharmacologic test；
◊ Toxicokinetics test；
◊ Local toxicity test (irritation test, allergy test, hemolytic test, phototoxicity test, etc.).

Advantage ability

◊ available in evaluation of cell products (stem cells, car-t, tcr-t, CTL, etc.)
◊ Dependency tests can be carried out
◊ More than 10 routes of administration can be evaluated
◊ Animal species involve rodents (mice, rats, guinea pigs, gopher), rabbits, miniature pigs, Beagle dogs, non-human primates (cynomolgus monkeys, rhesus monkeys), etc
◊ Providing neuropsychiatric drug evaluation, pediatric drug safety evaluation, inhaled drug safety evaluation
◊ There are the senior toxicology experts and the consultation team
◊ Data written

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